Anne-Clémence Vion

This study identifies NET1/ARHGEF8 as a mechanosensitive RhoGEF that regulates vascular smooth muscle cell contractility and adhesion in response to cyclic stretch.

This study shows that an ANGPTL6 variant causes vascular dysfunction and increases intracranial aneurysm risk in mice by disrupting matrix-bound ANGPTL6 function and integrin signaling.

The paper shows that zebrafish trunk vasculature balance is controlled by early genetic programming and flow-mediated adjustments.

This study shows YAP and TAZ regulate endothelial cell dynamics and vascular development by modulating junctions and signaling pathways.