Author

David J. Whittaker

University of NottinghamORCID 0000-0002-2757-5491Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:electrophysiology· 2 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:optimal transport· 1

Frequent Co-Authors

Chon Lok LeiiD· 2 shared Gary R. MiramsiD· 2 shared Adam Parker HilliD· 1 shared Matthew PerryiD· 1 shared Michael ClerxiD· 1 shared Monique J. WindleyiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 12 mutual co-author links

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2 shared papersBiophysics

Chon Lok LeiORCID

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2 papers

Recent·Most cited

BiophysicsWellcome Open ResearchPeer-reviewedNov 12, 2024

A range of voltage-clamp protocol designs for rapid capture of hERG kinetics

Chon Lok Lei, David J. Whittaker, Monique J. Windley…·Gary R. Mirams

The paper introduces voltage-clamp protocols for efficiently capturing hERG ion channel kinetics to aid in modeling.

1 citation

electrophysiologyexperimental assay

𝕏 PostBluesky

BiophysicsMathematics in Medical and Life SciencesPeer-reviewedJul 23, 2024

Optimal experimental designs for characterising ion channel gating by filling the phase-voltage space of model dynamics

Gary R. Mirams, Michael Clerx, David J. Whittaker, Chon Lok Lei

This paper introduces an optimal experimental design for ion channel gating characterization by efficiently exploring the phase-voltage space using hERG/Kv11.1 currents.

3 citations

electrophysiologyoptimal transport

𝕏 PostBluesky