Chon Lok Lei

This study optimizes voltage protocols to distinguish drug-binding mechanisms of hERG channels using synthetic data, showing improved model selection when the true model is known.

The paper evaluates the predictive accuracy of IKr ion channel models using voltage-clamp data from multiple experimental protocols and identifies parameter heterogeneity across cells.

The paper introduces voltage-clamp protocols for efficiently capturing hERG ion channel kinetics to aid in modeling.

This paper introduces an optimal experimental design for ion channel gating characterization by efficiently exploring the phase-voltage space using hERG/Kv11.1 currents.

This paper develops a computational model to identify and correct artefacts in voltage-clamp experiments, improving the accuracy of ion channel recordings.

This paper develops a method to automatically design optimal experimental protocols for calibrating cardiac electrophysiology models to better identify cell-specific parameters.