Honglei Wang

The paper reconstructs a rare Δ10 desaturation pathway in Camelina sativa to produce yellow peach moth pheromone precursors, achieving up to 4.7% target fatty acids in seeds.

This study shows that VAMP7 regulates mitochondrial-lysosome contacts in fly glia, affecting mitochondrial dynamics and dopaminergic neuron survival through Rab7 GTP hydrolysis.

This study identifies two new Atg9 phosphorylation sites, T62 and T69, that regulate autophagic trafficking in glia and contribute to Parkinson's disease pathology.

This study identifies dAux's role in regulating lysosomal V-ATPase assembly through phosphorylation, which is critical for α-synuclein degradation in glia and PD progression.

This study identifies GAK/dAux as a regulator of glial autophagy, showing it interacts with ULK1/Atg1 and modulates autophagosome formation and flux.

This study identifies a LRRK2/dLRRK-mediated lysosomal pathway in glia that contributes to glial cell death and dopaminergic neuron survival in Parkinson's disease.