Clancy W. Mullan

The paper identifies endothelial protein C receptor (EPCR) as an entry receptor for Langya and related parahenipaviruses and describes the structural basis of this interaction.

This study identifies oncostatin M-driven vascular leak in human endothelial cells through nanoscale channel formation, distinct from junction disassembly, and highlights potential therapeutic targets.

This study shows that C9, a component of membrane attack complexes, forms non-cytolytic intracellular aggregates that promote inflammation and EC activation through aggrephagy and NF-κB activation.