Nanoparticle Accumulation and Penetration in 3D Tumor Models: the Effect of Size, Shape, and Surface Charge
Pierre Cybulski, María Loreto Bravo, Jim Jui‐Kai Chen, Indra Van Zundert, Sandra Krzyzowska, Farsai Taemaitree, Hiroshi Uji‐i, Johan Hofkens, Susana Rocha, Beatrice Fortuni
This study evaluates how nanoparticle size, shape, and surface charge affect their accumulation and penetration in 2D and 3D tumor models, finding that larger, negatively charged, and spherical NPs perform best.
Frontiers in Cell and Developmental Biology · Jan 24, 2025Peer-reviewedCancer Biology