Sofie Degerman

A network approach to DNA methylation clocks

This paper uses a network approach to analyze DNA methylation clocks, revealing module structures that improve clock performance and transferability across platforms.

Profiling histone post-translational modifications to identify signatures of epigenetic drug response in T-cell acute lymphoblastic leukemia

The paper uses mass spectrometry to profile histone post-translational modifications in T-ALL cell lines and identifies drug response signatures, but finds discrepancies between in vitro and in vivo models.