The energetic stress cytokine GDF15 is elevated in the context of chronic and acute psychosocial stress
Qiuhan Huang, Anna Sophia Monzel, Shannon Rausser, Rachel Haahr, Claire Eckstein Indik, Micah J. Savin, Natalia Bobba‐Alves, Cynthia C. Liu, Jack Devine, Elizabeth Thompson, Catherine A. Kelly, Mangesh Kurade, Jeremy Michelson, Shufang Li, Kris Engelstad, , Caroline Trumpff
This paper shows that GDF15 levels rise with psychosocial stress, depression, anxiety, and biological aging, and that saliva GDF15 has a distinct diurnal pattern and responds rapidly to acute stress.
bioRxiv · Apr 19, 2024 · PreprintPhysiology