Cynthia C. Liu

This paper introduces a neuroimaging framework to map brain mitochondria non-invasively and finds age-related declines in mitochondrial density and respiratory capacity, along with disease-specific alterations and links to systemic stress and cognition.

The paper profiles mitochondrial phenotypes in immune cells of mitochondrial disease patients and finds they are largely preserved and not strongly linked to disease severity.

This study examines salivary GDF15 levels and their associations with biopsychosocial factors and stress reactivity in healthy adults.

The paper examines cf-mtDNA and GDF15 as potential biomarkers of mitochondrial health in aging, finding GDF15 correlates with age and diabetes while cf-mtDNA does not.

This paper shows that GDF15 levels rise with psychosocial stress, depression, anxiety, and biological aging, and that saliva GDF15 has a distinct diurnal pattern and responds rapidly to acute stress.