Author

Purnima Bhargava

Centre for Cellular and Molecular BiologyORCID 0000-0002-2787-5953Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Ashutosh ShuklaiD· 2 shared Dileep PullepuiD· 1 shared Dipti Vinayak Vernekar· 1 shared Gopalakrishnan Aneeshkumar ArimbasseriiD· 1 shared Kaustuv SanyaliD· 1 shared Kuladeep DasiD· 1 shared Kuljeet Singh SandhuiD· 1 shared Nikitha Kendyala· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Ashutosh ShuklaORCID

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2 papers

Recent·Most cited

Terminator-dependent facilitated recycling of RNA polymerase III couples transcriptional activation and chromatin remodeling in vivo

Vinesh Vinayachandran, Yatendra Kumar, Sushma Shivaswamy, Ashutosh Shukla, Nikitha Kendyala, Dileep Pullepu, Kuladeep Das, Kaustuv Sanyal, Purnima Bhargava

The paper shows that transcription terminators facilitate RNA polymerase III recycling, enhancing chromatin transcription and linking transcriptional activation with chromatin remodeling in vivo.

Science Advances · Aug 14, 2026Peer-reviewedMolecular Biology

Yeast PAF1 complex restricts the accumulation of RNA polymerase III and counters the replication stress on the transcribed genes

Pratibha Bhalla, Ashutosh Shukla, Dipti Vinayak Vernekar, Gopalakrishnan Aneeshkumar Arimbasseri, Kuljeet Singh Sandhu, Purnima Bhargava

The paper identifies the PAF1 complex as a regulator of RNA polymerase III transcription, showing it restricts pol III accumulation and reduces replication stress on transcribed genes.

Scientific Reports · Sep 9, 2019Peer-reviewedMolecular Biology