Author

Ashutosh Shukla

Centre for Cellular and Molecular BiologyORCID 0000-0002-7851-8817Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Purnima BhargavaiD· 2 shared Alexander M. TataraiD· 1 shared Angela J. RogersiD· 1 shared Ankita Sarkar· 1 shared Anoj IlangesiD· 1 shared Carolyn S. CalfeeiD· 1 shared Catherine CheniD· 1 shared David G. Thomas· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersMolecular Biology

Purnima BhargavaORCID

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3 papers

Recent·Most cited

Molecular BiologyScience AdvancesPeer-reviewedAug 14, 2026

Terminator-dependent facilitated recycling of RNA polymerase III couples transcriptional activation and chromatin remodeling in vivo

Vinesh Vinayachandran, Yatendra Kumar, Sushma Shivaswamy…·Purnima Bhargava

The paper shows that transcription terminators facilitate RNA polymerase III recycling, enhancing chromatin transcription and linking transcriptional activation with chromatin remodeling in vivo.

DOI 10.1126/sciadv.aeg6231

ChIP-seqDNA methylation

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PhysiologybioRxivPreprintApr 21, 2026

Lipid mobilization establishes metabolic tolerance and prevents autonomic collapse in infection

Ankita Sarkar, Shangkui Xie, Syed Kazim Rizvi…·Suraj J. Patel

This study identifies white adipose tissue lipolysis and circulating fatty acids as key mediators of metabolic tolerance to infection, showing improved survival in sepsis with beta3-adrenergic agonists.

DOI 10.64898/2026.04.16.717052

humanmouse

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Molecular BiologyScientific ReportsPeer-reviewedSep 9, 2019

Yeast PAF1 complex restricts the accumulation of RNA polymerase III and counters the replication stress on the transcribed genes

Pratibha Bhalla, Ashutosh Shukla, Dipti Vinayak Vernekar…·Purnima Bhargava

The paper identifies the PAF1 complex as a regulator of RNA polymerase III transcription, showing it restricts pol III accumulation and reduces replication stress on transcribed genes.

14 citations

yeastproteomics

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