Paracrine rescue of MYR1-deficient Toxoplasma gondii mutants reveals limitations of pooled in vivo CRISPR screens
Francesca Torelli, D. Matos da Fonseca, Simon Butterworth, Joanna C. Young, Moritz Treeck
The paper shows that MYR1-deficient Toxoplasma gondii mutants are rescued by co-infection with wild-type parasites in mice, revealing a limitation of pooled in vivo CRISPR screens.
eLife · Dec 10, 2024Peer-reviewedMicrobiology