Author

Vincent Lejour

Centre National de la Recherche ScientifiqueORCID 0000-0002-2797-1507Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1

Frequent Co-Authors

Eliana Eldawra· 2 shared Franck ToledoiD· 2 shared Jeanne RakotopareiD· 2 shared Anne Fajac· 1 shared Antonin MorilloniD· 1 shared Boris BardotiD· 1 shared Carla Jane DuvaliD· 1 shared Hugues EscoffieriD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

Eliana Eldawra

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Oncogenic and teratogenic effects of Trp53Y217C, an inflammation-prone mouse model of the human hotspot mutant TP53Y220C

Sara Jaber, Eliana Eldawra, Jeanne Rakotopare, Iva Simeonova, Vincent Lejour, Marc Gabriel, Tatiana Cañeque, Vitalina Volochtchouk, Monika Licaj, Anne Fajac, Raphaël Rodriguez, Antonin Morillon, Boris Bardot, Franck Toledo

This study shows that the p53Y217C mutation causes inflammation, leading to oncogenic effects in male mice and teratogenic effects in female mice, with anti-inflammatory treatment improving female survival.

eLife · Apr 14, 2025Peer-reviewedCancer Biology

A systematic approach identifies p53-DREAM target genes associated with blood or brain abnormalities

Jeanne Rakotopare, Vincent Lejour, Carla Jane Duval, Eliana Eldawra, Hugues Escoffier, Franck Toledo

The paper identifies 151 p53-DREAM target genes associated with blood or brain abnormalities through transcriptomic analysis and ChIP-seq data.

Disease Models & Mechanisms · Sep 4, 2023Peer-reviewedGenetics