Author

Hikaru Tsuchiya

Juntendo UniversityORCID 0000-0002-2797-6711Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Elena RyzhiiiD· 1 shared Gaoxin MaoiD· 1 shared Hideaki MorishitaiD· 1 shared Manabu AbeiD· 1 shared Masaaki KomatsuiD· 1 shared Michitaka SuzukiiD· 1 shared Mitsuyoshi NakaoiD· 1 shared Nozomi Shinomiya· 1 shared

Activity by Year

2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Elena RyzhiiORCID

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1 paper

Recent·Most cited

Cell BiologyEMBO ReportsPeer-reviewedMay 28, 2025

KEAP1 retention in phase-separated p62 bodies drives liver damage in autophagy-deficient conditions

Shuhei Takada, Nozomi Shinomiya, Gaoxin Mao…·Masaaki Komatsu

The paper shows that KEAP1 retention in p62 bodies and NRF2 activation cause liver damage when autophagy is impaired, and that blocking p62-KEAP1 interactions reduces this damage.

12 citations

mouseproteomics

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