BioengineeringMolecular Cancer TherapeuticsPeer-reviewed
In vivo Auto-tuning of Antibody-Drug Conjugate Delivery for Effective Immunotherapy using High-Avidity, Low-Affinity Antibodies
Anna Kopp, Shujun Dong, Hyeyoung Kwon…·Greg M. Thurber
This study develops HALA antibodies that adjust ADC delivery based on tumor HER2 expression, improving efficacy across varying expression levels in preclinical models.
9 citations