Adam J. Horn

Fibroblast response to burn injury in larval zebrafish mirrors developmental maturation and is inhibited by infiltrating neutrophils

Vimentin-driven maturation of col1a1a-positive fibroblasts after larval zebrafish burn parallels fin development, but prolonged neutrophil presence delays fibroblast maturation and organized collagen regrowth.

A conserved in vivo burn wound infection model for diverse pathogenic fungi.

This paper establishes a zebrafish burn wound model to study fungal colonization and host immune responses, finding that macrophages and neutrophils control fungal infection with some redundancy.

Live imaging in zebrafish reveals tissue-specific strategies for amoeboid migration

The paper uses live imaging in zebrafish to show T cells adapt their migration strategies based on tissue-specific geometries, using different actin structures in different environments.

Isotonic medium treatment limits burn wound microbial colonization and improves tissue repair

The paper shows isotonic medium treatment reduces epithelial damage spread and microbial colonization in burn wounds in larval zebrafish and human skin.