Kevin W. Eliceiri

The paper investigates how Rho and Cdc42 signaling zones form and polarize during cell repair in Xenopus oocytes, revealing a self-organized mechanism involving protein recruitment at signaling compartment overlaps.

Vimentin-driven maturation of col1a1a-positive fibroblasts after larval zebrafish burn parallels fin development, but prolonged neutrophil presence delays fibroblast maturation and organized collagen regrowth.

The paper shows how instructive inputs during a critical period shape neural circuits to enable effective credit assignment in learning.

This study physically optimizes T cells to enhance their ability to sample and engage with pancreatic ductal adenocarcinoma tumor cells, improving therapeutic outcomes.

This paper introduces a live tumor fragment platform to assess immunotherapy response in core needle biopsies, showing it can detect T-cell responses and mitigate tissue heterogeneity challenges.

This study uses semi-automatic image analysis to show late reperfusion therapy reduces infarct border size and accelerates healing phases in rat myocardium.

A 3D-printable device enables non-invasive, longitudinal imaging of adult zebrafish brains, revealing aging-associated changes in microglia dynamics.

This study uses a mouse model of TB infection to investigate fibrosis mechanisms, finding persistent inflammatory macrophages and elevated matrix remodeling enzymes during treatment.

This study uses real-time imaging in zebrafish to show that macrophage protrusive motility, regulated by Rac2, influences melanoma invasion.

The paper uses machine learning to analyze mid-infrared spectra for collagen detection in pancreatic tissues, achieving high accuracy compared to SHG microscopy.

Piximi provides a no-programming web tool for biological image analysis using deep learning, enabling rapid insights without installation or coding.

This study uses FLIM to analyze metabolic changes in microglia of 5XFAD mice, revealing increased glycolysis and a novel fluorescence component linked to AD pathology.

This study shows KLC4 is essential for axon branching and arborization in zebrafish sensory neurons and links it to anxiety-like behavior in adults.

The paper summarizes a survey of 484 bioimage analysis community members to identify needs for tools, training, and resources.

This paper introduces See-Shells, transparent polymer skulls that enable long-term optical access to the mouse cortex for simultaneous monitoring and perturbation of neural activity across multiple regions.