piRNA direct the chromatin reader to its genomic targets
Yicheng Luo, Wenjiang Zhou, Zhaohui Jin, Baira K. Godneeva, Xiawei Huang, Haoqing Wang, He Peng, Ying Huang, Alexei A. Aravin
The paper shows that Rhi recruitment to genomic targets in Drosophila is mediated by a combination of H3K9me3 binding and a piRNA-guided scaffold involving Panx and Kipf.
bioRxiv · May 9, 2026 · PreprintMolecular Biology