Developmental BiologyNature CommunicationsPeer-reviewed
Vegfa expression is activated through positive and negative transcriptional regulatory networks controlled by the ETS factor Etv6 in vivo
Lei Li, Rossella Rispoli, Roger K. Patient…·Catherine Porcher
The paper shows Etv6 regulates vegfa expression in Xenopus blood stem cells by both repressing foxo3 and activating klf4, with Klf4 recruiting Etv6 to the vegfa promoter.
19 citations