Author

Adriana Arruda Matos

Universidade de São PauloORCID 0000-0002-2823-7769Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Alina O. Oliveira· 1 shared Ana C Monteleone-CassianoiD· 1 shared Cíntia Júnia MonteiroiD· 1 shared Eduardo Antônio DonadiiD· 1 shared Ernna D. Oliveira· 1 shared Geraldo Aleixo Silva PassosiD· 1 shared Leticia Agrelli de Brito· 1 shared Max Jordan DuarteiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Alina O. Oliveira

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1 paper

Recent·Most cited

The ribonucleoprotein-mediated CRISPR-Cas9 system induces recurrent Aire gene mutations in contrast to the nickase expression vector in murine in vitro or in vivo models

Pedro Paranhos Tanaka, Cíntia Júnia Monteiro, Max Jordan Duarte, Ernna D. Oliveira, Ana C Monteleone-Cassiano, Romário S. Mascarenhas, Mayara Cristina Vieira-Machado, Adriana Arruda Matos, Leticia Agrelli de Brito, Alina O. Oliveira, Thiago M. Cunha, Eduardo Antônio Donadi, Geraldo Aleixo Silva Passos

The paper compares CRISPR-Cas9 RNP and nickase systems for inducing Aire gene mutations in murine mTECs, finding recurrent mutations with RNP but not nickase.

bioRxiv · Oct 13, 2023 · PreprintMolecular Biology