Author

Xu Cai

Beijing Tsinghua Chang Gung HospitalORCID 0000-0002-2827-0841Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Organism:mouse· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Fanlei HuiD· 1 shared Hao YaniD· 1 shared Huihui Yuan· 1 shared Jingyun Wang· 1 shared Le Jiang· 1 shared Leixin Liu· 1 shared Peixia Li· 1 shared Qichao Wang· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBioengineering

Fanlei HuORCID

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1 paper

Recent·Most cited

TREM2 agonist antibody rebuilds the resident synovial macrophage lining barrier in rheumatoid arthritis

Huihui Yuan, Jingyun Wang, Qichao Wang, Le Jiang, Leixin Liu, Weicheng Shen, Peixia Li, Wanting Liu, Ziyu Liu, Fanlei Hu, Xu Cai, Wanli Liu, Qiong Wu, Xiumei Wang, Hao Yan, Xiaodan Sun

This study shows that a TREM2 agonist antibody rebuilds the synovial macrophage lining barrier in RA by shifting macrophage states toward a barrier-like phenotype.

bioRxiv · Feb 5, 2026 · PreprintBioengineering