Cancer BiologybioRxivPreprint
The novel RNA polymerase I transcription inhibitor PMR-116 exploits a critical therapeutic vulnerability in a broad-spectrum of high MYC malignancies.
Rita Ferreira, Katherine M. Hannan, Kostya I. Panov…·Nadine Hein
This study shows PMR-116, a second-generation RiBi inhibitor, effectively targets high-MYC cancers without causing DNA damage, suggesting RiBi as a viable cancer therapy.
6 citations