Kostya I. Panov

This study shows that during nutrient starvation, chromatin accessibility decreases genome-wide, but RNA abundance increases selectively in stress-adaptive genes, indicating limited predictive power of ATAC-seq for transcript abundance.

This study shows PMR-116, a second-generation RiBi inhibitor, effectively targets high-MYC cancers without causing DNA damage, suggesting RiBi as a viable cancer therapy.

The paper identifies a shift in the active miRNA targetome in a mouse model of retinal degeneration, showing changes in miRNA binding regions and AGO2 localization.