Ayano Kondo

This study investigates the role of TNFSF13 in colonic epithelial cell-B cell interactions and finds that TNFSF13 insufficiency disrupts B cell differentiation and epithelial growth.

The paper uses spatial proteomics to analyze protein expression changes in human diabetic kidney disease across different stages, revealing compartment-specific cellular and inflammatory changes.

This work introduces SCGP, a method for unsupervised identification of tissue structures from spatial omics data, and demonstrates its application to spatial transcriptomics and proteomics datasets.

The paper maps the regulatory landscape of the mouse kidney at single cell resolution, identifying key transcription factors and regulatory circuits, and linking variants to kidney disease.