Author

Leigh A. Mickelson-Young

North Carolina State UniversityORCID 0000-0002-2848-4970Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1 Organism:plant (other)· 1 Research Focus:spatial domain detection· 1 Assay:spatial transcriptomics· 1

Frequent Co-Authors

Emily E. WeariD· 2 shared Linda K. Hanley-BowdoiniD· 2 shared William F. ThompsoniD· 2 shared Chantal LeBlanciD· 1 shared David O. DeppongiD· 1 shared George C. AlleniD· 1 shared Gregory J. ZyndaiD· 1 shared Hafiza Sara AkramiD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersGenetics

Emily E. WearORCID

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2 papers

Recent·Most cited

Replication Timing Uncovers a Two-Compartment Nuclear Architecture of Interphase Euchromatin in Maize

Hafiza Sara Akram, Emily E. Wear, Leigh A. Mickelson-Young, Zachary M. Turpin, Linda K. Hanley-Bowdoin, William F. Thompson, Lorenzo Concia, Hank W. Bass

The paper uses Hi-C and 3D FISH to show maize euchromatin has two distinct interphase subcompartments, early-S and middle-S, defined by replication timing and chromatin organization.

The Plant Cell · Feb 19, 2026Peer-reviewedGenetics

Comparing DNA replication programs reveals large timing shifts at centromeres of endocycling cells in maize roots

Emily E. Wear, Jawon Song, Gregory J. Zynda, Leigh A. Mickelson-Young, Chantal LeBlanc, Tae-Jin Lee, David O. Deppong, George C. Allen, Robert A. Martienssen, Matthew W. Vaughn, Linda K. Hanley-Bowdoin, William F. Thompson

The paper compares DNA replication timing in mitotic and endocycling cells in maize roots, finding significant shifts in centromere replication timing during the endocycle.

PLoS Genetics · Oct 14, 2020Peer-reviewedGenomics