William F. Thompson

The paper uses Hi-C and 3D FISH to show maize euchromatin has two distinct interphase subcompartments, early-S and middle-S, defined by replication timing and chromatin organization.

The paper compares DNA replication timing in mitotic and endocycling cells in maize roots, finding significant shifts in centromere replication timing during the endocycle.

Repliscan classifies replication timing regions from Repli-seq data by normalizing, filtering, and assigning replication signatures, outperforming previous methods with variable thresholds.