Emily E. Wear

Replication Timing Uncovers a Two-Compartment Nuclear Architecture of Interphase Euchromatin in Maize

The paper uses Hi-C and 3D FISH to show maize euchromatin has two distinct interphase subcompartments, early-S and middle-S, defined by replication timing and chromatin organization.

Comparing DNA replication programs reveals large timing shifts at centromeres of endocycling cells in maize roots

The paper compares DNA replication timing in mitotic and endocycling cells in maize roots, finding significant shifts in centromere replication timing during the endocycle.

Repliscan: a tool for classifying replication timing regions

Repliscan classifies replication timing regions from Repli-seq data by normalizing, filtering, and assigning replication signatures, outperforming previous methods with variable thresholds.