Author

Ikuhiro Okamoto

Kyoto UniversityORCID 0000-0002-2870-8321Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Mitinori SaitouiD· 3 shared Édith HeardiD· 2 shared Atsutaka Minagawa· 1 shared Belinda Kaswandy· 1 shared Bo WangiD· 1 shared Chizuru Iwatani· 1 shared Chongjian Chen· 1 shared Christel PicardiD· 1 shared

Activity by Year

2017-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersDevelopmental Biology

Mitinori SaitouORCID

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3 papers

Recent·Most cited

Developmental BiologyCell stem cellPeer-reviewedApr 7, 2021

Capturing Human Trophoblast Development with Naive Pluripotent Stem Cells In Vitro

Shingo Io, Mio Kabata, Yoshiki Iemura…·Yasuhiro Takashima

This study shows that naive human pluripotent stem cells can recapitulate trophoblast development in vitro, producing cells that resemble human placental trophoblasts.

281 citationstop 1%

humanexperimental assay

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Systems BiologyNature Structural & Molecular BiologyPeer-reviewedApr 8, 2019

A symmetric toggle switch explains the onset of random X inactivation in different mammals

Verena Mutzel, Ikuhiro Okamoto, Ilona Dunkel…·Edda G. Schulz

The paper identifies a symmetric toggle switch as the mechanism for random Xist up-regulation during X-chromosome inactivation in mammals.

53 citations

mousestatistical model

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Developmental BiologyNature CommunicationsPeer-reviewedOct 30, 2017

Differential epigenetic landscapes and transcription factors explain X-linked gene behaviours during X-chromosome reactivation in the mouse inner cell mass

Maud Borensztein, Ikuhiro Okamoto, Laurène Syx…·Édith Heard

The paper investigates X-linked gene reactivation in mouse inner cell mass by analyzing epigenetic marks and transcription factors, finding differential reactivation speeds and mechanisms.

73 citations

mousebulk RNA-seq

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