Author

Chizuru Iwatani

Shiga University of Medical Science

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 4 Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Organism:non-human primate· 3 Research Focus:cell-cell communication· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:spatial domain detection· 2

Frequent Co-Authors

Hideaki Tsuchiya· 4 shared Tomoyuki TsukiyamaiD· 4 shared Mitinori SaitouiD· 3 shared Masataka Nakaya· 2 shared Prachiti MogheiD· 2 shared Takafumi IchikawaiD· 2 shared Takashi HiiragiiD· 2 shared Adrian WolnyiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersDevelopmental Biology

Hideaki Tsuchiya

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6 papers

Recent·Most cited

Adolescent prodromal phenotypes of psychiatric disorders: insights from a novel DISC1-perturbed monkey model

Ziguo Lan, Hirotaka Onoe, Tomoyuki Tsukiyama, Chizuru Iwatani, Chih-Yang Chen, Keisuke Okita, Koko Ishizuka, Ryo Endo, Risako Nakai, Keiko Imamura, Keigo Hikishima, Hideaki Tsuchiya, Masataka Nakaya, Yang Fang, Atsushi Kobayashi, , Tadashi Isa

This paper presents a novel monkey model with impaired DISC1 gene to study adolescent prodromal phenotypes of psychiatric disorders, finding altered social behavior and disrupted brain connectivity.

bioRxiv · Oct 18, 2026 · PreprintNeuroscience

Atlas of Cynomolgus Macaque Hematopoiesis

Shinichiro Oshima, Rahul Sinha, Kazuhiro Takeuchi, Ken Mizuta, Tomonori Nakamura, Ryoji Ito, Ikuo Kawamoto, Chizuru Iwatani, Masataka Nakaya, Hideaki Tsuchiya, Shruti Bhagat, Tomoyuki Tsukiyama, Akifumi Takaori‐Kondo, Mitinori Saitou, Yasuhiro Murakawa, Ryō Yamamoto

The paper develops a single-cell transcriptomic map of cynomolgus macaque hematopoietic stem cells and progenitors, revealing molecular differences from humans and a direct differentiation pathway to megakaryocyte lineages.

Experimental Hematology · Nov 1, 2025Peer-reviewedCell Biology

Apical-driven cell sorting optimised for tissue geometry ensures robust patterning

Prachiti Moghe, Roman Belousov, Takafumi Ichikawa, Chizuru Iwatani, Tomoyuki Tsukiyama, François Graner, Anna Erzberger, Takashi Hiiragi

The paper shows apical polarity in PrE cells drives robust tissue patterning in blastocysts by guiding migration and breaking symmetry.

Nature Cell Biology · Feb 18, 2025Peer-reviewedDevelopmental Biology

Temporal variability and cell mechanics control robustness in mammalian embryogenesis

Dimitri Fabrèges, Bernat Corominas‐Murtra, Prachiti Moghe, Alison Kickuth, Takafumi Ichikawa, Chizuru Iwatani, Tomoyuki Tsukiyama, Nathalie Daniel, Julie Gering, Anniek Stokkermans, Adrian Wolny, Anna Kreshuk, Véronique Duranthon, Virginie Uhlmann, Édouard Hannezo, Takashi Hiiragi

The paper shows that stochastic division timing and cell mechanics contribute to robust embryo patterning and morphogenesis in mammals.

Science · Oct 10, 2024Peer-reviewedDevelopmental Biology

The developmental origin and the specification of the adrenal cortex in humans and cynomolgus monkeys

Keren Cheng, Yasunari Seita, Taku Moriwaki, Kiwamu Noshiro, Yuka Sakata, Young Sun Hwang, Toshihiko Torigoe, Mitinori Saitou, Hideaki Tsuchiya, Chizuru Iwatani, Masayoshi Hosaka, Toshihiro Ohkouchi, Hidemichi Watari, Takeshi Umazume, Kotaro Sasaki

The paper identifies the adrenal cortex's origin in adrenogenic coelomic epithelium, distinct from gonadogenesis, in humans and cynomolgus monkeys.

Science Advances · Apr 20, 2022Peer-reviewedDevelopmental Biology

Capturing Human Trophoblast Development with Naive Pluripotent Stem Cells In Vitro

Shingo Io, Mio Kabata, Yoshiki Iemura, Katsunori Semi, Nobuhiro Morone, Atsutaka Minagawa, Bo Wang, Ikuhiro Okamoto, Tomonori Nakamura, Yoji Kojima, Chizuru Iwatani, Hideaki Tsuchiya, Belinda Kaswandy, Eiji Kondoh, Shin Kaneko, , Yasuhiro Takashima

This study shows that naive human pluripotent stem cells can recapitulate trophoblast development in vitro, producing cells that resemble human placental trophoblasts.

Cell stem cell · Apr 7, 2021Peer-reviewedDevelopmental Biology