Author

Sergio Espinosa-Gil

Universitat Autònoma de BarcelonaORCID 0000-0002-2873-8475Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Alexandra Arias· 1 shared Almudena Neva-AlejoiD· 1 shared Ariadna Grinyo i EscueriD· 1 shared Barbara A. SteccaiD· 1 shared Cayetano Galera Martinez· 1 shared Cesar Merino Allona· 1 shared Claudia Faundez VidiellaiD· 1 shared Dario Solis Sayago· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

Alexandra Arias

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ERK5 inhibition triggers CDK6 proteasomal degradation and enhances palbociclib efficacy in cancer cells

Claudia Faundez Vidiella, Ylenia Sfragano, Ignazia Tusa, Barbara A. Stecca, Sergio Espinosa-Gil, José Miguel Lizcano, Elisabetta Rovida

This study shows that inhibiting ERK5 causes CDK6 degradation and enhances palbociclib's effectiveness in melanoma and endometrial cancer cells.

bioRxiv · Sep 18, 2026 · PreprintCancer Biology

C1q from C1q+ tumor-associated myeloid cells promotes resistance to T-cell engagers and CAR T-cells and is induced by LIF and glucocorticoids

María López Vázquez, Sergio Espinosa-Gil, Raffaella Iurlaro, Laura Carrillo Bosch, Ariadna Grinyo i Escuer, Dario Solis Sayago, Alexandra Arias, Isabel Cuartas, Almudena Neva-Alejo, Laia Cuesta‐Casanovas, Ester Bonfill‐Teixidor, Cayetano Galera Martinez, Cesar Merino Allona, Maria Duarte Leon, Irepan Salvador‐Martínez, , Joan Seoane

This study identifies C1q from C1q+ tumor-associated myeloid cells as a key immunosuppressive factor in glioblastoma that impairs T-cell engagers and CAR T-cell efficacy, induced by LIF and glucocorticoids.

bioRxiv · Sep 17, 2026 · PreprintCancer Biology