Eamonn P. Duffy

This study identifies strain-dependent genetic influences on oxycodone self-administration patterns in rats, revealing differences in acquisition, escalation, and burst-like responding.

This study shows that voluntary oxycodone self-administration in rats leads to analgesic tolerance and sex-dependent hyperalgesia, with genetic strain differences in thermal sensitivity and analgesic response.

This study shows that sex and genetic background affect oxycodone self-administration in rats, with heritability estimates ranging from 0.25 to 0.54.