Marissa A. Ehringer

This study shows that acute nicotine exposure induces a spatially organized transcriptional response in mouse olfactory cortex, affecting specific neurons and their surrounding astrocytes.

This study identifies strain-dependent genetic influences on oxycodone self-administration patterns in rats, revealing differences in acquisition, escalation, and burst-like responding.

This study shows that voluntary oxycodone self-administration in rats leads to analgesic tolerance and sex-dependent hyperalgesia, with genetic strain differences in thermal sensitivity and analgesic response.

The paper investigates the role of AKT2 in astrocytic nicotine responses, showing it modulates morphological changes and nicotine preference in mice.

This study shows that sex and genetic background affect oxycodone self-administration in rats, with heritability estimates ranging from 0.25 to 0.54.

This study introduces a method to analyze gene-gene interactions across multiple traits and tissues, identifying novel associations and pathways through transcriptome-wide interaction studies.

The paper tests whether genes identified in mouse anxiety models are associated with human anxiety disorders using genome-wide association studies.

The paper estimates SNP-based heritability for four smoking behaviors using partitioned h2SNP in the UK Biobank, finding modest heritability and significant contributions from low-frequency variants.

The paper replicates main effects of rs16969968 and age of smoking onset on smoking quantity but fails to replicate their interaction effect.

The paper assesses the association of two gene sets with smoking behaviors using GWAS data and finds they contribute little to the heritability of these traits.