BiophysicsbioRxivPreprint
A Rapid and Universal Pipeline for High-Resolution GPCR Structure Determination through In Silico Construct Optimization and de novo Protein Design
Asato Kojima, Kouki Kawakami, Naoya Kobayashi…·Hideaki E. KATO
This paper introduces a pipeline combining AI-assisted construct screening and de novo protein design to rapidly determine high-resolution GPCR structures, validated on multiple receptors.