Mark H. Kaplan

This study shows that type I interferon signaling is critical for early control of Borrelia burgdorferi infection by enhancing macrophage function and immune cell recruitment, but contributes to inflammation later in infection.

This study shows that local oxygen levels affect hematopoietic cell growth, metabolism, and potency, with low oxygen preserving less proliferative, stress-resistant cells.

This study shows mast cells promote epithelial-to-mesenchymal transition in colorectal cancer through direct contact and integrin-mediated signaling.

This study investigates respiratory IgA responses after SARS-CoV-2 infection, vaccination, or hybrid immunity, showing that mucosal booster vaccination enhances IgA and protective immunity.

This study identifies MCP5 as essential for Borrelia burgdorferi's immune evasion and transmission, regulated by two signaling pathways.