Author

Francis G. Szele

University of OxfordORCID 0000-0002-2931-0673Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Yichen LiiD· 2 shared Alan Mackay‐SimiD· 1 shared Alexandre S. CristinoiD· 1 shared Angela J. RusselliD· 1 shared Anna Hoerder‐SuabedisseniD· 1 shared Anthony C. JamesiD· 1 shared Bin SuniD· 1 shared Blanca TorrobaiD· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersNeuroscience

Yichen LiORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Phenotypic screen-based discovery of a small molecule that can increase adult neurogenesis and improve memory

Julie Davies, Anna Hoerder‐Suabedissen, Ksenia Musaelyan, Blanca Torroba, Jesse Daubney, Nicole Untermoser, Tom Carter, Ulrich Stefan Bauer, Roderick Walker, Kate S. Harris, Liam J. Bromhead, Megalakshi Suresh, Penelope Fouka, Yichen Li, Steve Davies, , Francis G. Szele

This study identifies a small molecule, OXS-N1, that increases adult neurogenesis and improves memory in a mouse model of Alzheimer's disease through an in vitro phenotypic screen.

bioRxiv · Jul 27, 2023 · PreprintNeuroscience

Adolescent-onset and adult-onset schizophrenia: reduced ribosomal protein expression via mTOR signalling in patient-derived olfactory cells

Yichen Li, Melanie Föcking, Alexandre S. Cristino, Jane English, Gerard Cagney, Anthony C. James, David Cotter, Francis G. Szele, Alan Mackay‐Sim

This study compares proteomic profiles of olfactory cells from adolescent- and adult-onset schizophrenia patients, finding similar downregulation of ribosomal proteins and mTOR pathway components.

bioRxiv · Aug 26, 2020 · PreprintNeuroscience

Paupar LncRNA Promotes KAP1 Dependent Chromatin Changes And Regulates Subventricular Zone Neurogenesis

Ioanna Pavlaki, Farah Alammari, Bin Sun, Neil Clark, Tamara Sirey, Sheena Lee, Dan J. Woodcock, Chris Paul Ponting, Francis G. Szele, Keith W. Vance

The paper identifies Paupar, a lncRNA that interacts with KAP1 to regulate chromatin structure and neurogenesis in the subventricular zone.

The EMBO Journal · Apr 16, 2018Peer-reviewedNeuroscience