Timothy R. Billiar

The paper identifies rare SNPs associated with hypo-inflammation and adverse outcomes in trauma patients, highlighting type 17 immune responses as central to critical illness.

This paper describes a mouse model with a human ADAR G1007R mutation that causes neuroinflammation and shows that deleting MDA5 can reverse brain inflammation.

The paper identifies molecular and spatial features of early liver transplant rejection, including primed T-cells, immune synapse activation, and novel drug targets like proteasomal and HSP90 inhibitors.