Author

Milena Simovic-Lorenz

German Cancer Research CenterORCID 0000-0001-8835-6885Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Aurélie ErnstiD· 2 shared Agata Rode· 1 shared Andreas KienzleiD· 1 shared Angelika Beate RiemeriD· 1 shared Anna Sophia JauchiD· 1 shared Christoph PlassiD· 1 shared Daniel HaagiD· 1 shared Frauke Devens· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

Aurélie ErnstORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintJul 30, 2025

Integrative spatial and multi-omic profiling in bladder cancer links L1 retrotransposition to extrachromosomal DNA, genomic instability, and viral mimicry response

Sophia J. Pribus, Ivana Osredek, Jan Otoničar…·Aurélie Ernst

This study integrates spatial and multi-omic data from bladder cancer patients to show L1 retrotransposition drives genomic instability, ecDNA formation, and a viral mimicry response.

2 citations

humanscRNA-seq

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GenomicsGenes Chromosomes and CancerPeer-reviewedJul 31, 2020

A versatile system to introduce clusters of genomic double-strand breaks in large cell populations

Thorsten Kolb, Umar Khalid, Milena Simovic-Lorenz…·Aurélie Ernst

This paper introduces a method to generate localized DNA double-strand breaks in cell populations using UV-irradiation with photomasks, enabling the study of genome rearrangements and DNA damage response.

5 citations

humanDNA methylation

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