Author

Pablo Bousquets‐Muñoz

Institute of Cancer ResearchORCID 0000-0002-2969-008XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:Bayesian inference· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

Agnieszka Graczyk‐JarzynkaiD· 1 shared Andrei Thomas‐TikhonenkoiD· 1 shared Calum GabbuttiD· 1 shared Carlo C. MaleyiD· 1 shared Darryl ShibataiD· 1 shared Diego MalloiD· 1 shared Emmanuelle Benard· 1 shared Heather E. GrantiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperImmunology

Agnieszka Graczyk‐JarzynkaORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

PHYFUM: Phylogenetic Reconstruction of Normal and Pre-malignant Tissue Evolution Using Fluctuating Methylation

Pablo Bousquets‐Muñoz, Heather E. Grant, Darryl Shibata, Trevor A. Graham, Carlo C. Maley, Calum Gabbutt, Diego Mallo

PHYFUM reconstructs the evolutionary history of normal and pre-malignant tissues using methylation data, revealing early gland divergence in the gut and later divergence in the endometrium.

bioRxiv · May 7, 2026 · PreprintBioinformatics

The costimulatory domain influences CD19 CAR-T cell resistance development in B-cell malignancies.

Marta Krawczyk, Narcís Fernández‐Fuentes, Klaudyna Fidyt, Tomasz Winiarski, Monika Pępek, Agnieszka Graczyk‐Jarzynka, Jacinta Davis, Pablo Bousquets‐Muñoz, Xosé S. Puente, Pablo R. Menéndez, Emmanuelle Benard, Sébastien Wälchli, Andrei Thomas‐Tikhonenko, Magdalena Winiarska

This study identifies that the costimulatory domain of CD19-CAR-T cells influences resistance development in B-cell malignancies by affecting CD19 loss and antigen escape.

bioRxiv · Feb 28, 2025 · PreprintImmunology