Author

Jacinta Davis

Children's Hospital of Philadelphia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Assay:scRNA-seq· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Andrei Thomas‐TikhonenkoiD· 2 shared Adam Cain ResnickiD· 1 shared Adanna Mogbo· 1 shared Agnieszka Graczyk‐JarzynkaiD· 1 shared Alvin FarreliD· 1 shared Ammar S. NaqviiD· 1 shared Annette CastroiD· 1 shared Berk Mankaliye· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

Andrei Thomas‐TikhonenkoORCID

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2 papers

Recent·Most cited

NRCAM variant defined by microexon skipping is a targetable cell surface proteoform in high-grade gliomas

Priyanka D. Sehgal, Ammar S. Naqvi, Makenna Higgins, Jia‐Geng Liu, Kyra Harvey, Julien Jarroux, Tae Woo Kim, Berk Mankaliye, Pamela Mishra, Grace Watterson, Justyn Fine, Jacinta Davis, Katharina E. Hayer, Annette Castro, Adanna Mogbo, , Andrei Thomas‐Tikhonenko

The paper identifies a NRCAM proteoform with skipped microexons as a targetable surface antigen in pHGG and demonstrates its utility in immunotherapy.

Cell Reports · Aug 1, 2025Peer-reviewedCancer Biology

The costimulatory domain influences CD19 CAR-T cell resistance development in B-cell malignancies.

Marta Krawczyk, Narcís Fernández‐Fuentes, Klaudyna Fidyt, Tomasz Winiarski, Monika Pępek, Agnieszka Graczyk‐Jarzynka, Jacinta Davis, Pablo Bousquets‐Muñoz, Xosé S. Puente, Pablo R. Menéndez, Emmanuelle Benard, Sébastien Wälchli, Andrei Thomas‐Tikhonenko, Magdalena Winiarska

This study identifies that the costimulatory domain of CD19-CAR-T cells influences resistance development in B-cell malignancies by affecting CD19 loss and antigen escape.

bioRxiv · Feb 28, 2025 · PreprintImmunology