Peter J. Grahn

Segment-specific orientation of the dorsal and ventral roots for precise therapeutic targeting of human spinal cord

This study provides the first detailed analysis of segment-specific dorsal and ventral spinal roots orientation in humans, correlated with spinal cord and vertebral landmarks.

Newly regenerated axons through a cell-containing biomaterial scaffold promote reorganization of spinal circuitry and restoration of motor functions with epidural electrical stimulation.

This study shows that a cell-containing biomaterial scaffold promotes axon regeneration and spinal circuit reorganization, enhancing motor function recovery when combined with epidural electrical stimulation after spinal transection.

Multifactorial motor behavior assessment for real-time evaluation of emerging therapeutics to treat neurologic impairments

This paper introduces a novel method to assess motor behavior in rodents by integrating electrophysiological, biomechanical, and behavioral metrics during therapeutic interventions.