Author

Meghan A. Wynosky-Dolfi

University of PennsylvaniaORCID 0000-0002-2985-3918Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Andy J. MinniD· 1 shared Emily AuninsiD· 1 shared Igor E. BrodskyiD· 1 shared James P. GrayczykiD· 1 shared Luying Liu· 1 shared Marisa S. EganiD· 1 shared Scott CannaiD· 1 shared Sunny ShiniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 28 mutual co-author links

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1 shared paperMolecular Biology

Andy J. MinnORCID

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1 paper

Recent·Most cited

TLR priming licenses NAIP inflammasome activation by immunoevasive ligands

James P. Grayczyk, Luying Liu, Marisa S. Egan, Emily Aunins, Meghan A. Wynosky-Dolfi, Scott Canna, Andy J. Minn, Sunny Shin, Igor E. Brodsky

This study shows TLR priming increases NLRC4 expression in murine macrophages, enabling detection of immunoevasive NAIP ligands, while human macrophages lack this response.

Proceedings of the National Academy of Sciences · Nov 18, 2024Peer-reviewedMolecular Biology