Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewed
TLR priming licenses NAIP inflammasome activation by immunoevasive ligands
James P. Grayczyk, Luying Liu, Marisa S. Egan…·Igor E. Brodsky
This study shows TLR priming increases NLRC4 expression in murine macrophages, enabling detection of immunoevasive NAIP ligands, while human macrophages lack this response.