Author

Keisuke Sako

National Cerebral and Cardiovascular Center Research InstituteORCID 0000-0002-6453-8075Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:zebrafish· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1

Frequent Co-Authors

Naoki MochizukiiD· 4 shared Hiroyuki NakajimaiD· 3 shared Moe FukumotoiD· 3 shared Ayano ChibaiD· 2 shared Haruko Watanabe‐TakanoiD· 2 shared Ning Gui· 2 shared Akihiro YasodaiD· 1 shared Ankita SharmaiD· 1 shared

Activity by Year

2019-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersDevelopmental Biology

Naoki MochizukiORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Developmental BiologyDevelopmental CellPeer-reviewedNov 11, 2025

Endothelial-zippering proceeds by sensing heartbeat-driven force through Cadherin-6 during heart-vessel connection in zebrafish

Moe Fukumoto, Haruko Watanabe‐Takano, Hajime Fukui…·Naoki Mochizuki

DOI 10.1016/j.devcel.2025.10.011

zebrafishexperimental assay

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Cell BiologyCell Structure and FunctionPeer-reviewedJan 1, 2025

Chemokine induces phase transition from non-directional to directional migration during angiogenesis

Ning Gui, Keisuke Sako, Moe Fukumoto…·Hiroyuki Nakajima

This study shows chemokine signaling induces a phase transition in tip cells during angiogenesis, shifting migration from non-directional to directional.

DOI 10.1247/csf.24081

zebrafishimaging

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Developmental BiologyDevelopmentPeer-reviewedMay 14, 2024

Angpt1 binding to Tie1 regulates the signaling required for lymphatic vessel development in zebrafish

Nanami Morooka, Ning Gui, Koji Ando…·Hiroyuki Nakajima

The paper identifies Angpt1/Tie1 signaling as essential for trunk lymphatic vessel development in zebrafish, showing Tie1 regulates Foxo1 localization and modulates Vegfc/Vegfr3 signaling.

8 citations

zebrafishexperimental assay

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Developmental BiologyNature CommunicationsPeer-reviewedOct 19, 2021

Satb2 acts as a gatekeeper for major developmental transitions during early vertebrate embryogenesis

Saurabh J. Pradhan, Puli Chandramouli Reddy, Michael Smutny…·Sanjeev Galande

The paper investigates the role of Satb2 in regulating zygotic genome activation and developmental transitions during vertebrate embryogenesis, showing distinct maternal and zygotic functions.

19 citations

mousebulk RNA-seq

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Developmental BiologybioRxivPreprintJul 9, 2019

Periosteum-derived Osteocrin regulates bone growth through both endochondral ossification and intramembranous ossification

Haruko Watanabe‐Takano, Hiroki Ochi, Ayano Chiba…·Naoki Mochizuki

This study shows that Osteocrin promotes both endochondral and intramembranous ossification in long bone growth by enhancing CNP signaling.

2 citations

mouseexperimental assay

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