David M. Underhill

Fungal microbial enrichment method enables fungal metagenomics directly from human clinical samples

This paper introduces fMEM, a fungal microbial enrichment method that enables direct fungal metagenomic analysis from clinical samples, recovering MAGs with high completeness and resolving clinically relevant genes.

Commensal Yeast Promotes Salmonella Typhimurium Virulence

This study shows that the commensal fungus Candida albicans enhances Salmonella Typhimurium virulence by promoting arginine production, which in turn boosts Salmonella's ability to invade host cells and dampens the host's inflammatory response.

The intestinal microbiota contributes to the development of immune-mediated cardiovascular inflammation and vasculitis in mice.

This study shows that gut microbiota depletion reduces cardiovascular inflammation in a mouse model of Kawasaki disease, and specific bacteria or their metabolites can alleviate vasculitis by improving gut barrier function.