Rustem F. Ismagilov

Fungal microbial enrichment method enables fungal metagenomics directly from human clinical samples

This paper introduces fMEM, a fungal microbial enrichment method that enables direct fungal metagenomic analysis from clinical samples, recovering MAGs with high completeness and resolving clinically relevant genes.

Ultra-low biomass sequencing workflow (LBV-Seq) enables de novo metagenomic reconstruction of DNA and RNA viral genomes

LBV-Seq enables de novo reconstruction of DNA and RNA viral genomes from low-input samples, achieving broad genome coverage and resolving strains and gene-level variation.

Faecalibacterium prausnitzii, depleted in the Parkinson's disease microbiome, improves motor deficits in α-synuclein overexpressing mice

Oral Faecalibacterium prausnitzii, the taxon most consistently depleted in PD stool, improved motor and GI deficits and lowered α-synuclein aggregates in male Thy1-ASO mice.

Inducible, but not constitutive, pancreatic REG/Reg isoforms are regulated by intestinal microbiota and pancreatic diseases

The paper investigates differences in REG/Reg isoform expression and regulation in pancreas and gut, finding inducible isoforms are regulated by microbiota and pancreatic diseases.

A single-cell method to map higher-order 3D genome organization in thousands of individual cells reveals structural heterogeneity in mouse ES cells