Xianjin Zhou

This study shows that IgM anti-NMDAR1 autoantibodies improve cognitive functions like sensorimotor gating and fear extinction in mice, contrasting with IgG's negative effects.

This paper develops a new immunoassay to quantify low-titer blood anti-NMDAR1 autoantibodies and validates it against existing methods in humans and mice.

The paper identifies SP4 as a schizophrenia-risk gene and shows its role in regulating other risk genes through GC-boxes in their promoters.

This study shows that chronic low-titer blood circulating anti-NMDAR1 autoantibodies impair spatial working memory in mice, suggesting potential cognitive effects in humans.