Victoria B. Risbrough

This study shows early-life unpredictability affects decision-making under uncertainty by increasing discounting and overharvesting, distinct from lifelong stress effects.

This study shows that IgM anti-NMDAR1 autoantibodies improve cognitive functions like sensorimotor gating and fear extinction in mice, contrasting with IgG's negative effects.

This study examines how early-life unpredictability affects hippocampal and amygdala responses to novelty in adolescents, finding sex-specific differences in brain activation and functional connectivity.

This paper develops a new immunoassay to quantify low-titer blood anti-NMDAR1 autoantibodies and validates it against existing methods in humans and mice.

This study shows that chronic low-titer blood circulating anti-NMDAR1 autoantibodies impair spatial working memory in mice, suggesting potential cognitive effects in humans.

This study shows that Reelin deficiency exacerbates long-term behavioral issues in mice exposed to THC during adolescence, including impaired social behavior and increased novelty seeking.

This study identifies genetic variants associated with self-reported childhood maltreatment and finds significant genetic correlations with depressive symptoms.

The paper performs a meta-analysis of DNA methylation data from military cohorts to identify CpG sites and regions associated with PTSD development.

This study identifies ten novel methylation loci associated with PTSD through a meta-analysis of 1,896 cases and controls across ten cohorts, highlighting the AHRR locus and its link to kynurenine levels.

The paper identifies SNRNP35 as a trauma type-specific PTSD gene through analysis of genetically regulated gene expression in PTSD cases and controls.

This study identifies shared and sex-specific inflammatory pathways in PTSD through a meta-analysis of blood transcriptomes across different trauma types and biological sexes.