Susan B. Powell

This study shows that maternal immune activation disrupts DNA methylation and transcriptome of cortical excitatory neurons, delaying their maturation and affecting synapse-related genes.

This study shows that IgM anti-NMDAR1 autoantibodies improve cognitive functions like sensorimotor gating and fear extinction in mice, contrasting with IgG's negative effects.

The paper maps protein-protein interactions of schizophrenia risk factors in rodent brains, revealing an interconnected disease network and showing how PCP perturbations alter these interactions.

This paper develops a new immunoassay to quantify low-titer blood anti-NMDAR1 autoantibodies and validates it against existing methods in humans and mice.

This study shows nicotine promotes GABAergic neurons to adopt a dopaminergic phenotype, reducing alpha-synuclein-induced motor deficits in Parkinson's models.

This study shows that Dnmt3a knockout in mouse excitatory neurons disrupts synapse maturation and working memory, with partial compensation by H3K27me3.

The paper uses microPET imaging to show that gp120 transgenic mice exhibit heightened neuroinflammation in response to LPS compared to wildtype mice, mirroring HIV-related hypersensitivity in PLWH.

This study shows that chronic low-titer blood circulating anti-NMDAR1 autoantibodies impair spatial working memory in mice, suggesting potential cognitive effects in humans.