Tarmo Äijö

This study creates a spatial and cellular atlas of the colon across age groups using spatial transcriptomics and single nucleus RNA-seq, identifying age-related molecular gradients and multicellular programs.

This study shows TET2 and TET3 regulate Drosha and microRNAs in iNKT cells, linking DNA demethylation to gene expression and lineage specification.

CRISPR-Decryptr analyzes noncoding CRISPR screens to infer regulatory elements by accounting for experimental design and validating on published data.

This paper introduces HDST, a high-resolution spatial transcriptomics method, and demonstrates its application in mouse brain tissue to resolve spatial expression patterns and cell types.

Splotch aligns spatial transcriptomics data across tissue sections and timepoints to improve gene expression estimates and study optimal experimental design.

Analysis of the ALS spinal cord using Spatial Transcriptomics reveals spatiotemporal dynamics of disease driven gene regulation.