Transcriptional profile of pyramidal neurons in chronic schizophrenia reveals lamina-specific dysfunction of neuronal immunity
Xiaojun Wu, Rammohan Shukla, Khaled Alganem, Erica A. K. DePasquale, James K. Reigle, Micah S. Simmons, Chang-Gyu Hahn, Vahram H. Haroutunian, Jarek Meller, James H. Meador‐Woodruff, Robert Erne McCullumsmith
The paper identifies lamina-specific gene expression changes in pyramidal neurons from schizophrenia patients compared to controls, highlighting immune and synaptic pathway disruptions.
Biological Psychiatry · May 1, 2020Peer-reviewedNeuroscience